Flavonoid research hasn’t been possible until recently. Flavonoids are a naturally-occurring compound that’s found in plants, fruits, and vegetables, accounting for their brilliant, diverse coloring. Cannabis flavonoids were discovered in 1986 by Marilyn Barrett and were later found to promote anti-inflammatory advantages. Since flavonoids are only 0.14% of the cannabis plant, researchers were not capable of further studying the benefits. With new technological advancements, scientists are now able to genetically engineer cannabis flavonoids. The Dana-Farber Cancer Institute from Harvard University recently released its findings for flavonoids and pancreatic cancer.

Cannabis Compound’s Promising Effects on Pancreatic Cancer

Researchers chose FBL-03G, a specific drug that’s derived from a cannabis flavonoid. In their lab experiment, they tested its impact on pancreatic cancer cells. Pancreatic cancer is predicted to be the second deadliest cancer by 2020, with a 20% one-year survival rate. Researchers found promising conclusions– the flavonoid-derived drug was able to kill both local and metastatic tumor cells, providing an increased survival rate from pancreatic cancer. On top of successfully killing those cancer cells, the drug also inhibited the growth of other cancer cells in parts of the body that weren’t initially targeted in the experiment. Wilfred Ngwa PhD, an assistant professor at Harvard and one of the scientists in this study, stated, “This suggests that the immune system is involved as well, and we are currently investigating this mechanism.”

Future Research on Flavonoids and Pancreatic Cancer

Since pancreatic cancer usually isn’t diagnosed until later stages once it’s spread, this development may prove to be capable of killing other cancer cells as well, helping improve the survival rate. The Dana-Farber Cancer Institute plans on completing their preclinical trials by 2020 and hopefully successfully translate this clinically. We look forward to the future of cannabis research!

For more information on flavonoid research and other recent cannabis studies, please contact us!

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